Allergy is a common hypersensitivity condition worldwide. It can be treated by allergen-specific immunotherapies (AIT). Natural allergen extracts do not fulfill the regulatory requirements for allergy vaccine manufacturing, which are unstable and have varying amounts of allergens, contamination, and poor immunogenicity.

Recombinant allergens are genetically engineered isoforms representing allergen molecules from allergen extracts, which opened up new avenues for the diagnosis and research of human allergic diseases.
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