The use of commercial animal DNA tests for breed identification and ancestry has become increasingly popular with pet owners in recent years.
However, these at-home DNA tests for dogs, cats, and other companion animals have some important limitations that consumers should understand.
How Do Animal DNA Tests Work?
Companies provide breed identification kits that typically involve collecting a cheek swab DNA sample from your pet at home. You then mail the swab to the company's laboratory where they analyze your pet's genetic markers. Breed DNA tests work by detecting differences in sections of DNA called "markers" that tend to be associated with certain breeds. By comparing your pet’s DNA to their large proprietary databases of breed-specific genetic signatures, they make statistical estimates for breed makeup.
Breed identification from DNA is very accurate for purebred dogs with well-defined genetic profiles in the company’s database. However, accuracy tends to decrease for mixed breed animals that have more genetic diversity or uncommon breed signatures that may be absent from the testing company’s comparisons. Hence, there is a high demand for Animal DNA Testing Service.
Potential Limitations of Commercial Animal DNA Tests
While genetic Animal DNA Testing Service can provide useful breed ancestry information for your cat or dog, these consumer tests do have some limitations, including:
- Limited breed databases: Even large proprietary breed databases do not contain every pure and mixed breed that could appear in your pet's background. A DNA company may not have the genetic signatures required to accurately identify more obscure contributing breeds.
- Assessment of limited genetic markers: Most routine dog or cat DNA tests assess only 100-200 informative genetic markers. Whole genome sequencing assessing billions of DNA base pairs could provide more accuracy but remains prohibitively expensive for consumer tests.
- Lack of peer-reviewed validation studies: There has been little third-party evaluation in scientific literature about the real-life accuracy of most commercial animal DNA breed tests, especially for complex mixed breed dogs. More validation would improve confidence in testing accuracy.
- Different results from different companies: Comparing breed composition results from different DNA testing companies for the same dog or cat often shows dramatic differences. This indicates a clear limitation as they can’t all be highly accurate at the same time.
- Inheritance randomness affects sibling results: Breed tests for related dogs from the same litter often yield different breed compositions due to the random nature of how chromosomes and genetic markers are inherited.
- Limited information on health and disease risk: While some higher-end dog DNA kits like Embark assess common genetic disease risks like cancer or heart disease, most routine commercial breed tests provide no information on inherited health conditions.
- Detects breeds only: These tests identify statistical breed composition in your pet’s ancestry. But they do not reconstruct full pedigree or prove descent from any specific purebred ancestor dogs claimed by a breeder nor verify official breed registration eligibility.
How Accurate Are These Tests for Predicting Dog Breeds?
Overall, consumer DNA tests from reputable companies can accurately detect most predominant breeds contributing to a mixed breed dog with a fair degree of confidence if those signature breed markers exist in their comparison database. However, when it comes to more distant minor contributor breeds that left only a small genetic fingerprint, their detection accuracy is lower.
For a mixed breed with 5+ potential ancestral breeds across parents and grandparents, most dog DNA kits may provide correctly identified breeds only around 60-85% of the time when compared to their known lineage. Detection accuracy is even lower for less common rare breeds not well-represented in the minimal genetic marker databases.
Interpreting Your Pet’s DNA Results
It is important to interpret consumer DNA breed identification results for your cat or dog with reasonable expectations and understanding of these realistic testing limitations.
If a reported high confidence breed signature exceeds 15-20% of your pet's total composition in results from a well-established DNA company like Wisdom or Embark, it is very likely that breed contributed meaningfully to your companion animal's genetic makeup.
Lower confidence breed detections in the 5-15% range could indicate interesting but very distant ancestry several generations back that left only a small DNA fingerprint. However, minor contributor results below 10% have high odds of being false positive errors beyond the reliability of current consumer tests. Give less weight to these small single digit low confidence percentage breeds reported.
Also recognize that due to the intricacies of recombined genetics, your pet’s outward physical appearance offers only weak correlation with their internal breed composition genetics. Do not expect your cat or dog to visually look like all reported contributing source breeds indicated in DNA panel results. Phenotype appearance and genotype DNA markers reveal different aspects of ancestry.
You can upload your pet’s DNA breed composition results from companies like Wisdom Panel and Embark to public databases like DoggieDNA.com to help connect with other owners whose pets share similar breed mixture backgrounds. This crowdsourced data from testing across millions of user dogs provides external validation unlikely breed results are true rather than false positives.
Should You Test Your Puppy or Kitten’s DNA?
At-home genetic testing offers pet owners intriguing but imperfect supplemental information about their dog or cat’s likely breed ancestry and family tree. Rapidly dropping costs and improving databases will likely enhance accuracy over time. Consumer DNA tests provide some entertaining insight. However, it should not be interpreted as definitive proof your pet descends from specific purebred ancestors without further validation.
Both cats and dogs with well-documented multi-generational pedigrees from reputable breeders do not necessarily need breed identification testing unless confirming details on unexpected diversity. However, DNA screening can still satisfy curiosity.
For adopted shelter animals, lack of ancestral record makes consumer DNA screening more meaningful to explore possible breed composition as part of better understanding your pet’s background. But even with the best available dog or cat DNA test kits, recognize realistic reliability limits the farther back testing tries to detect more distant minor ancestral breed contributors for a mixed animal.
Final Words
Consult your veterinarian if curious whether specialized genetic screening for inherited disease identification or predisposition ever makes sense as a health-focused supplement to routine DNA breed tests documenting pedigree. Advanced selection of specific disease risk panels tailored to your dog or cat’s suspected ancestry can uncover valuable information about genetic susceptibility.